Headline acts Messi and Ronaldo bid farewell to World Cup

Portugal forward Cristiano Ronaldo

Cavani was replaced by Cristhian Stuani for the remainder of the game as Uruguay held on to their 2-1 lead and secured a quarter-final fixture with France.

Ronaldo, however, appears energised whenever he wears the Portuguese badge on his chest.

Portugal coach Fernando Santos knew the question about Portugal's dependence on Ronaldo was coming, and said he even won a coffee because of it after making a bet with the team's press officer ahead of Friday's news conference.

"Cristiano still has a lot to give to football", said Santos.

Portugal's defeat saw Cristiano Ronaldo's hopes of lifting the World Cup ended, just hours after Lionel Messi and Argentina suffered the same fate against France.

While Real Madrid's Ronaldo will also be bitterly disappointed to be heading home earlier than planned from Russian Federation, he at least has the consolation of having won his country's first ever European Championship, two years ago in France.

Ronaldo does not have to shoulder the same burden.

Ronaldo helped Portugal to glory at EURO 2016 in France but watched much of the final from the sidelines after suffering an injury.

Uruguay won all three of their group matches, beating hosts Russian Federation 3-0 in their last outing, and are the only team yet to concede a goal at the tournament.

However, Uruguay soon led again when Cavani curled in a peach of a finish, though his delight soon turned to anguish as the striker limped off after appearing to pull a muscle. Both the teams are in a great form and both the nations are considered a big name in football.

He had scored just one goal in each of the last two World Cups in South Africa and Brazil, and both came in losing efforts.

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Portugal had 61 percent of the possession and four times as many shots at goal as the Uruguayans, but Tabarez dismissed possession as a mere statistic and said what mattered was creating and converting chances. So, what are his targets?

Portugal defeated Morocco in the second match by 1-0 and drew against Iran by 1-1.

How Godin and Gimenez fare against Ronaldo is one of the intriguing subplots surrounding this fixture, though both sides' defensive records have some fearing a boring contest. At the very least, you can bet that Ronaldo will want to break the 100-goal barrier for his country.

"A rivalry with Ronaldo here (at the World Cup) and at a club level are two different things".

Ronaldo nearly had a chance at goal on 20 minutes but a timely clearance by Gimenez six yards was enough to keep Ronaldo at bay.