Del Potro sets up Federer clash at US Open quarters

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Argentina's injury-prone Juan del Potro overcame a slow start to beat Austria's Dominic Thiem in five sets 1-6, 2-6, 6-1, 7-6 (7/1), 6-4.

He won one game and had two break points at 5-1 but Thiem, who was looking to book his spot in the last eight here for the first time, coolly closed out the set.

Even though it was a singles match, there were two winners and one loser on Wednesday afternoon.

"Thanks so much for all the support you gave", del Potro told the boisterous Grandstand crowd that regaled the 24th-seeded Argentine with "Ole!" chants.

Monday was a microcosm of del Potro's history.

Rublev was shaky from the first game and double faulted twice en route to gifting Nadal - who had won his 50th US Open match in the previous round - a first break.

Federer can change that by winning his quarterfinal against Juan Martin del Potro later Wednesday.

"Obviously (del Potro) has everything to win and nothing to lose", said Wilander, who is at the US Open as analyst for Eurosport. Thiem's second serve was initially called good, but del Potro challenged, and the review showed the serve was out, ending the match.

Roger Federer defeated Philipp Kohlschreiber in straight sets to reach the quarter-finals of the US Open but there were more concerns about the 36-year-old's fitness.

His 23 winners on Monday were just shaded by world number 64 Dolgopolov's 25 but the Ukrainian's 39 unforced errors were more than three times those committed by Nadal.

She fed off the energy of the partisan crowd, which erupted when Pliskova returned a serve into the net on match point.

"I think I played a solid match", the 31-year-old Nadal said afterward. "It was her first time on Ashe so I tried to take advantage of that".

"He combines awesome points with mistakes".

The USTA says it will match donations encouraged from spectators at the U.S. Open by Connors, who is raising money at the tournament site by signing autographs and posing for photos with fans.

Rublev became the youngest Open quarterfinalist since Andy Roddick in 2001. The South African has a semi-final against No 12 seed Pablo Carreno-Busta.

Karolina Pliskova, the top seed for the women, made short work of unseeded American Jennifer Brady on Monday. The Czech Republic native is in the quarterfinals for the second consecutive year.

Women's quarterfinals: No. 9 Venus Williams beat No. 13 Petra Kvitova 6-3, 3-6, 7-6 (2); Sloane Stephens beat No. 16 Anastasija Sevastova 6-3, 3-6, 7-6 (4).

With Federer 36 and Nadal 31, the future remains very uncertain, but if they do finally meet here in NY, it will be not only a duel for a place in the final but a duel for the No. 1 ranking, now held by Nadal.

He raced to a 4-0 lead in the second as Del Potro looked completely out of sorts.

Vandeweghe, having conquered her fear of majors, is inching ever closer to the head of the gifted USA women hoping to crack the Grand Slam code.

At 5-0, he took a tablet.