But aides to Democrats - they are the minority party in both the House and Senate - said negotiations were continuing.
The House had passed the measure in July 2015, but disagreements over funding and persistent clamor against the landmark bill stalled it in the Senate. It will advance President Obama's personalized medicine initiative, Vice-President Biden's cancer moonshot, Alzheimer's research and move many treatments and cures more rapidly and safely through the regulatory process and into doctors' offices.
House Speaker Paul Ryan (R-Wis.) said the measure "is going to be a game-changer", adding, "It will fundamentally transform the way that we treat and cure diseases in this country".
Healthcare stakeholders have touted the health IT provisions of the bill, particularly regarding the Food and Drug Administration's (FDA) oversight of the sector, as well as encouraging interoperability of electronic health records (EHRs) and patient access to health data, and discouraging information blocking.
The bill also aims to improve mental health programs, including integrating mental health services into primary care settings and expanding access to mental health treatment and services. It is unclear if that funding would continue if the ACA were repealed, as President-elect Donald Trump and Congressional Republicans have vowed to do as quickly as possible. While "the bill is not ideal, and there are provisions the Administration would prefer were improved, the legislation offers advances in health that far outweigh these concerns", according to a statement issued by Office of the Press Secretary. This could mean that patient feedback which would now not be accepted as valid under current clinical standards could be used to help move drugs into the marketplace more quickly.
One of Warren's chief complaints concerned funding for federal agencies such as the National Institutes of Health - which, she said, amounted to just a "fig leaf" compared to what was initially requested. It has $1.8 billion for seeking a cure for cancer, a priority for Vice President Joe Biden, whose son Beau died of the disease a year ago.
The cures legislation also includes a mental health portion that seeks to reorganize and improve accountability for government mental health programs.
"We didn't get everything we needed", said Rep. Tim Murphy, R-Pa., sponsor of those provisions. It also authorizes $500 million in new FDA funding over the next 10 years to implement the changes, although that money would have to be appropriated in future legislation.
Hands out special deals to GOP donors: A major Republican donor to Mitch McConnell's Super PAC has big business plans to sell unsafe, unproven stem cell treatments before they have been approved by the FDA as safe and effective.
Provide $1 billion in grants to states to address the opioid crisis.
"There's no doubt that patients would like to get treatments faster to the market, but they need to be assured those treatments are safe and effective for each of those marketed uses", Carome says.
"I am pleased with provisions that allow the Food and Drug Administration (FDA) to streamline the approval of regenerative therapeutic products and encourage the FDA to identify opportunities for accelerated approval without lowering the current standards of evidence". Although Alexander will remain chairman of his committee next year, Upton will have to step down.
Some details of the measure are still being hammered out to appease Senate Democrats, but a final version is expected to be put to a vote on Wednesday.